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  • ¿Cómo pensar como Sherlock Holmes? - Maria Konnikova September 25, 2017
    Ningún personaje de ficción es más conocido por sus poderes de intuición y observación que Sherlock Holmes. Pero, ¿es su inteligencia extraordinaria una invención de la ficción o podemos aprender a desarrollar estas habilidades, para mejorar nuestras vidas en el trabajo y en casa? A través de ¿ Cómo pensar como Sherlock Holmes? , la periodista y psicóloga Ma […]
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  • Sapiens - Yuval Noah Harari September 25, 2017
    New York Times Bestseller A Summer Reading Pick for President Barack Obama, Bill Gates, and Mark Zuckerberg From a renowned historian comes a groundbreaking narrative of humanity’s creation and evolution—a #1 international bestseller—that explores the ways in which biology and history have defined us and enhanced our understanding of what it means to be “hum […]
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  • La teoría del todo - Stephen W. Hawking September 25, 2017
    Una manera clara y amena de acercarse a los misterios del universo. En esta esclarecedora obra, el gran físico británico Stephen Hawking nos ofrece una historia del universo, del big bang a los agujeros negros. En siete pasos, Hawking logra explicar la historia del universo, desde las primeras teorías del mundo griego y de la época medieval hasta las más com […]
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  • Sobre la teoría de la relatividad especial y general - Albert Einstein September 25, 2017
    Entre el Electromagnetismo y la Mecánica newtoniana existe una fórmula de bisagra: la teoría de la relatividad especial y general. La importancia del nuevo marco planteado por Albert Einstein se entiende por lo siguiente: la percepción del tiempo y el espacio es relativa al observador. ¿Qué significa esto? Si usted viaja a una velocidad mayor que la de la lu […]
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  • El gran diseño - Stephen Hawking & Leonard Mlodinow September 25, 2017
    Aun antes de aparecer, este libro ha venido precedido, en todos los medios de comunicación, de una extraordinaria polémica sobre  sus conclusiones: que tanto nuestro universo como los otros muchos universos posibles surgieron de la nada, porque su creación no requiere de la intervención de ningún Dios o ser sobrenatural, sino que todos los universos pro […]
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  • Breve historia de mi vida - Stephen Hawking September 25, 2017
    La mente maravillosa de Stephen Hawking ha deslumbrado al mundo entero revelando los misterios del universo. Ahora, por primera vez, el cosmólogo más brillante de nuestra era explora, con una mirada reveladora, su propia vida y evolución intelectual. Breve historia de mi vida cuenta el sorprendente viaje de Stephen Hawking desde su niñez […]
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  • La física del futuro - Michio Kaku September 25, 2017
    Un recorrido asombroso a través de los próximos cien años de revolución científica. El futuro ya se está inventando en los laboratorios de los científicos más punteros de todo el mundo. Con toda probabilidad, en 2100 controlaremos los ordenadores a través de diminutos sensores cerebrales y podremos mover objetos con el poder de nuestras mentes, la inteligenc […]
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  • Tricks Any Dog Can Do! - Susan Day September 25, 2017
    This great book comes with advice and guidance as to the best way to teach these tricks. It offers more than one method which the reader can choose depending upon their own situation. There is also advice to using treats and shows you how to not end up with a treat junkie! This books is from the desk of Susan Day, a canine behaviourist. Susan teaches obedien […]
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  • Ágilmente - Estanislao Bachrach September 25, 2017
    Bachrach es Doctor en biología molecular y explica el funcionamiento del cerebro. A través de ello, da consejos y herramientas para ser más creativos y felices en el trabajo y en la vida. La neurociencia es clara: el cerebro aprende hasta el último día de vida. La creatividad puede expandirse. Tu mente, mediante la aplicación de las técnicas correctas, puede […]
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  • El cisne negro. Nueva edición ampliada y revisada - Nassim Nicholas Taleb September 25, 2017
    ¿Qué es un cisne negro? Para empezar, es un suceso improbable, sus consecuencias son importantes y todas las explicaciones que se puedan ofrecer a posteriori no tienen en cuenta el azar y sólo buscan encajar lo imprevisible en un modelo perfecto. El éxito de Google y You Tube, y hasta ell 11-S, son “cisnes negros”. Para Nassim Nicholas Taleb, los cisnes negr […]
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North Korea Hits New Level of Brinkmanship in Reacting to Trump

North Korea has often issued statements in the names of its government and its People’s Army, and since taking power in late 2011, Mr. Kim has delivered an annual New Year’s Day speech […]

California Today: California Today: Amid Housing Pain, Most Californians Have Weighed a Move

Supported byU.S.California Today: Amid Housing Pain, Most Californians Have Weighed a MovePhotoA housing development in Oakland. The median cost of a home in California is now more than twice the national cost.Credit Justin Sullivan/Getty ImagesGood morning.(Want to get California Today by email? Here’s the sign-up.)The San Francisco Bay Area is often trotted out as the worst example of the state’s housing crisis — understandably.By national standards, rents and home prices there are astronomical.But the pain in California is widespread.According to a new poll from U.C. Berkeley, a majority of residents in every major region of the state — including the Central Valley and other parts of Northern California — have considered moving as a result of housing pressures.“It’s spread across the state pretty evenly,” said Mark DiCamillo, director of the Berkeley Institute of Governmental Studies Poll.Newsletter Sign UpContinue reading the main storyCalifornia TodayThe news and stories that matter to Californians (and anyone else interested in the state). […]

Forced Searches of Phones and Laptops at U.S. Border Are Illegal, Lawsuit Claims

David Lapan, a spokesman for the Department of Homeland Security, said he could not comment on pending litigation but that “we absolutely believe the searches are lawful.”In March, Joseph B. Maher, the acting general counsel for the agency, defended the practice in a USA Today opinion piece.“These electronic media searches have produced information used to combat terrorism, violations of export controls, and convictions for child pornography, intellectual property rights violations and visa fraud,” he wrote. “This authority is critical to our mission, and Customs exercises it judiciously.”While police officers on the street cannot compel you to hand over your phone without probable cause, border agents can search and confiscate digital devices as easily as they can your luggage […]

North Korea Used Multiple-Rocket Launchers to Test Missiles

The Pacific Command previously said that two of the North Korean missiles had “failed in flight.” But that assessment was later retracted, and the amended view agreed with the South Korean military’s evaluation of the distance the projectiles had traveled.The three missiles were 300-millimeter rockets fired from a multiple-tube launcher, said Yoon Young-chan, a spokesman at the Blue House, South Korea’s presidential office, where the country’s National Security Council met on Saturday to discuss the tests.North Korea has alarmed South Korean defense officials before with tests of its 300-millimeter rockets and displays of an eight-tube version of the system during military parades. The officials say the North has developed the multiple-tube launchers because they are cheaper than short-range, Scud-type ballistic missiles and because they enable more projectiles to be fired.GraphicCan North Korea Actually Hit the United States With a Nuclear Weapon?Six systems that North Korea needs to master to achieve a long-sought goal: being able to reliably hit the United States.OPEN GraphicNorth Korea keeps thousands of rocket launchers, as well as long-range artillery pieces, along the border with the South, threatening to rain down a “sea of fire” on South Korean cities and islands near the border. The old 240-millimeter rockets have an estimated range of 37 miles, putting Seoul, a capital with 10 million people, within reach.Kim Dong-yub, a defense analyst at the Institute for Far Eastern Studies at Kyungnam University in Seoul, said the tests on Saturday appeared to be aimed at expanding the strike range.Nevertheless, the nature of the tests prompted some relief in the region.The missiles flew to the northeast, not toward Guam, home to major United States Air Force and Navy bases. North Korea threatened to launch ballistic missiles in a “ring of fire” around Guam after President Trump threatened to hit the North with “fire and fury” if it persisted with its development of ICBMs.Newsletter Sign UpContinue reading the main storyThank you for subscribing.An error has occurred […]

Trump’s Tough Talk on North Korea Puts Japan’s Leader in Delicate Spot

figure.prepend(style); }); }); “The D.P.R.K. has already acquired the capabilities of reducing the Japanese archipelago to ashes in a second once it makes up its mind,” the North’s state news agency said an a statement accompanying the Guam plan, using the initials for the country’s official name, the Democratic People’s Republic of Korea. Japan is already moving to strengthen its antimissile defenses, and officials are debating whether to acquire weapons like long-range cruise missiles that would allow the country to strike targets in North Korea, either in retaliation or pre-emptively if it concluded that an attack by the North was imminent. Deploying such weapons would break with decades of precedent, and the idea is contentious. In keeping with the pacifist Constitution, Japan’s military is meant to protect the country from direct attack, while its partner the United States handles offensive duties like striking enemy bases — a so-called shield and spear arrangement. Most Japanese appear happy with that division of labor, despite concerns about North Korea, and Mr. Abe needs to tread carefully if he hopes to change it. The prime minister’s approval ratings have tumbled in recent months, specialists say, in part because voters believe he is overreaching in his efforts to roll back restrictions on the military, including with controversial proposed changes to the Constitution […]

Behind the Sudden Death of a $1 Billion Secret C.I.A. War in Syria

The program did have periods of success, including in 2015 when rebels using tank-destroying missiles, supplied by the C.I.A. and also Saudi Arabia, routed government forces in northern Syria. But by late 2015 the Russian military offensive in Syria was focusing squarely on the C.I.A.-backed fighters battling Syrian government troops. Many of the fighters were killed, and the fortunes of the rebel army reversed.Charles Lister, a Syria expert at the Middle East Institute, said he was not surprised that the Trump administration ended the program, which armed and trained thousands of Syrian rebels. (By comparison, a $500 million Pentagon program that envisioned training and equipping 15,000 Syrian rebels over three years, was canceled in 2015 after producing only a few dozen fighters.)“In many ways, I would put the blame on the Obama administration,” Mr. Lister said of the C.I.A. program. “They never gave it the necessary resources or space to determine the dynamics of the battlefield. They were drip-feeding opposition groups just enough to survive but never enough to become dominant actors.”Mr. […]

In Breakthrough, Scientists Edit a Dangerous Mutation From Genes in Human Embryos

“We’ve always said in the past gene editing shouldn’t be done, mostly because it couldn’t be done safely,” said Richard Hynes, a cancer researcher at the Massachusetts Institute of Technology who co-led the committee. “That’s still true, but now it looks like it’s going to be done safely soon,” he said, adding that the research is “a big breakthrough.”“What our report said was, once the technical hurdles are cleared, then there will be societal issues that have to be considered and discussions that are going to have to happen. Now’s the time.”Scientists at Oregon Health and Science University, with colleagues in California, China and South Korea, reported that they repaired dozens of embryos, fixing a mutation that causes a common heart condition that can lead to sudden death later in life.If embryos with the repaired mutation were allowed to develop into babies, they would not only be disease-free but also would not transmit the disease to descendants.The researchers averted two important safety problems: They produced embryos in which all cells — not just some — were mutation-free, and they avoided creating unwanted extra mutations.“It feels a bit like a ‘one small step for (hu)mans, one giant leap for (hu)mankind’ moment,” Jennifer Doudna, a biochemist who helped discover the gene-editing method used, called CRISPR-Cas9, said in an email.Gene Editing in EmbryosScientists tried two techniques to remove a dangerous mutation. In the first, genetic “scissors” were inserted into fertilized eggs. The mutation was repaired in some of the resulting embryos but not always in every cell. The second method worked better: By injecting the “scissors” along with the sperm into the egg, more embryos emerged with repaired genes in every cell.FIRST TECHNIQUEWhen gene-editing components were introduced into a fertilized egg, some embryos contained a patchwork of repaired and unrepaired cells.Gene-editingcomponents insertedafter fertilizationCell withunrepairedgeneMaternal DNAMutationSpermPaternal DNACell withrepairedgeneOocyteFertilized cellMosaicism inlater-stage embryoNEW TECHNIQUEWhen gene-editing components were introduced with sperm to the egg before fertilization, more embryos had repaired mutations in every cell.Gene-editing componentsinserted together with sperm,before fertilizationIn 42 of 58embryostested, allcells wererepairedUniformlater-stage embryoFIRST TECHNIQUEWhen gene-editing components were introduced into a fertilized egg, some embryos contained a patchwork of repaired and unrepaired cells.Gene-editingcomponents insertedafter fertilizationMaternal DNAMutationPaternalDNASpermOocyteFertilizedcellCell withunrepairedgeneCell withrepairedgeneMosaicism inlater-stage embryoNEW TECHNIQUEWhen gene-editing components were introduced with sperm to the egg before fertilization, more embryos had repaired mutations in every cell.Gene-editingcomponents insertedtogether with sperm,before fertilizationIn 42 of 58embryostested, allcells wererepairedUniformlater-stage embryo“I expect these results will be encouraging to those who hope to use human embryo editing for either research or eventual clinical purposes,” said Dr. Doudna, who was not involved in the study.Continue reading the main storyMuch more research is needed before the method could be tested in clinical trials, currently impermissible under federal law. But if the technique is found to work safely with this and other mutations, it might help some couples who could not otherwise have healthy children.Potentially, it could apply to any of more than 10,000 conditions caused by specific inherited mutations. […]